Virus of hepatitis C

The virus of hepatitis C is small a wrapped virus, of approximately 60 Nm diameter, whose genome is a linear ARN monocaténaire of positive polarity contained in an icosahedral proteinic capsid. It has a great genetic variability: six different genotypes were identified. Its prevalence in France and Belgium east of 1%; it goes up until more than 10% in certain areas D Africa (Egypt for example). Its mode of transmission is primarily parenteral (puncture, abrasion,…) and to a lesser extent sexual.

Its known Co-receivers are glycosaminoglycanes, SR-B1, CD81 and the Claudine 1.

The various genotypes constitute the Hepacivirus , and cause the Hépatite C.

In France, 650.000 people are carrying the VHC, but 400.000 do not know it.

References

  • Natural 446,801-805 (12 April 2007)

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