Transaminase
A transaminase or aminotransférase is a Enzyme which catalyze a type of reaction between an Amino-acid and a α-ketonic acid.
Enzyme with pyridoxal phosphate of the class of the Transférase S, it carries out the transfer of a grouping - NH2 of an amino-acid towards another, allowing the synthesis of new amino-acids, nonpresent in the medium.
Its Coenzyme is vitamin B6 (phosphorylée, which will give the pyridoxal phosphate).
This enzyme has a complex of co-ordination number with an ion coppers II.
Reaction of transfer of the grouping - NH2 is done by successive delocalizations of double connections, of which one leads to a Base of Schiff.
Transaminases are present in all fabrics, but they are often dependant with pathologies of the Myocarde (infarction) or Foie (necroses, hepatitis). In these cases, the enzymes arrive at circulation and their serum levels are increased.
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