Tizoc , “that which is bled” (its name is an allusion to a rite of autosacrifice) in language Nahuatl, is the older brother and successor of Axayacatl. It assembles on the throne towards 1481 to died of his brother for a rather short reign of approximately five years. It is a sovereign more peaceful than his predecessors, although it seizes the cities of Tuxpan and Yanhuitlan , but he is true that the Aztèques must be raised of an enormous military disaster vis-a-vis the Tarasques in 1478 under the reign of Axayacatl. Tizoc orders the construction of the Pierre of the Sacrifices , an imposing sculpture which represents the making emperor of the prisoners.

Towards 1486, after only five years of reign Tizoc east seems it assassinated, apparently poisoned, during a reaction peerage-book whose one is unaware of the precise causes.