Tim Hunt

Sir Richard Timothy (Tim) Hunt (born the February 19th 1943 in Neston in the Wirral, close to Liverpool) is a Biochimiste English. Jointly with Sir Paul Mr. Nurse and Leland H. Hartwell it accepted in 2001 the Nobel Prize of physiology or medicine for its work on the regulation of the cellular Cycle by the cyclines and the cycline-dependant Protein-kinases (Cdk).

After having attended the School Dragon and Magdalen School College with Oxford, Sir Tim Hunt obtains in 1968 its Ph.D. with the Université of Cambridge. In summer 1982, whereas the weather worked with the Laboratoire of biology marinades (MBL) with Woods Hole, in the Massachusetts, Sir Tim Hunt was most important of his lucky finds: by studying the cellular Cycle eggs of the sea urchin Arbacia punctulata , it discovered the cyclines. Sir Tim Hunt showed that the levels of these Protéines increased in egg of the moment of its Fécondation with the Interphase, to strongly fall at the time of the Mitose and the cellular Division, before again going up at the time of the Interphase cells girls, and so on, recurringly. It also found that these Protéine S played a part in the regulation of the cellular Cycle not only at the echinodermatous S, but also at the Vertébrés. Thereafter, and others showed to him that the cyclines bind and activate a family of regulating proteins currently called the cycline-dependant Protein-kinases (or Cdk, according to the abbreviation anglophone of cycline-dependant kinases ), of which one in particular was shown by Sir Paul Nurse| to have a crucial role in the regulation of the cellular Cycle.

Since 1991 Sir Tim Hunt worked with Imperial Cancer Research Fund (today Cancer Research the U.K., London Research Institute, in Great Britain). In 1991 he became member of the Royal Society, then in 1999 member of the National Academy off Sciences of the the United States. In 2006, Sir Tim Hunt was anobli by the queen Elizabeth II for her services with science.

References

  • the Nobel Prize . 2002. The Nobel Prizes 2001, Editor Frängsmyr Torus. Nobel Foundation: Stockholm.

External bonds

  • prizes winner of the Nobel Prize of medicine and physiology 2001
  • Autobiography on the site of the foundation Nobel

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