Syndrome of Brooks

The syndrome of Brooks is defined classically by the appearance of a asthmatic disease after a single accidental respiratory exposure to an irritant with strong concentrations.

This syndrome, described by Brooks and Al in 1985 , was named in English Reactive Airways Dysfunction Syndrome (RADS) and in French " syndrome of reactive dysfunction of the ways aériennes".

8 criteria define this syndrome:

  • respiratory Absence of antecedent

  • Occurred of the symptoms after a single exposure
  • Exposure to gases or smoke irritating present in very high concentration
  • Symptomatology occurring in the 24 hours and persisting more than 3 months after the exposure
  • Symptomatologie asthmatiforme with cough, sibilance and dyspnea
  • Possible obstructive ventilatory disorder with respiratory functional exploration
  • positive Test of procovation to the méthacholine, testifying to a nonspecific bronchial hyperreactivity
  • Absence of another bronchopulmonary etiology

The evolution is marked by:

  • a cure supplements in 50% of the cases
  • a stabilization of the lesions in 25% of the cases
  • an evolution of the bronchospasticity in 25% of the cases.

See too

  • http://www.inrs.fr/INRS-PUB/inrs01.nsf/IntranetObject-accesParReference/TR+25/$File/tr25.pdf Syndrome of Brooks, asthmas induced by the irrritants, INRS, n°82, 2000.

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