Syndrome of Bickerstaff

The syndrome of Bickerstaff is a disease dysimmunitaire central Nervous system. Following the example Syndrome of Miller-Fisher, to which it is very close, this syndrome is characterized by the presence in the blood of anti-GQ1B autoantibody, one of the components of the Myéline. However, these antibodies are found only at 70% of the patients suffering from Bickerstaff. For some, a virus of the kind Herpesviridae could be implied.

Symptomatology

Join:

Ophtalmoplégie (the Nerf S reached in the ophtalmoplégie are richest in GQ1B)
of others turbid ophthalmologic
aréflexie
of the signs of attack of the cerebral trunk
not of disorders of walk (contrary to Miller-Fisher, which produces an ataxia)

Treatment

It is the same one as that of the inflammatory polyradiculonévrite acute of Guillain-Barred-Strohl. It consists of immunoglobulinothérapie intravenous (a kind of serotherapy) or then exchanges plasmatic and especially prevention-treatment of the complications (like the disorders of swallowing, the dysautonomy, the disorders respiratory or the complications of Décubitus).

Random links: