Suppressor T

A cell T helper (or cell TH ) is a cell T (a type of Leucocyte) which has on its surface of the antigenic receivers which can bind to the fragments of Antigène associated with the molecules of Class II MHC (MHC = major histocompatibility complex) which are on the cells specialized in the presentation of antigens (APC).

Once bound to the antigen, the TH cells proliferate and are different in activated TH cells and storage cells TH .

  • the activated TH cells secrete cytokines, proteins or peptides which stimulate other lymphocytes; most current is the interleukine-2 (IL-2), which is a powerful growth factor of the Once activated cells T., TH cells and proliferating can be different in two principal sub-types, the Th1 cells and Th2. These sub-types are defined according to the specific cytokines that they produce. The Th1 cells produce interféron-gamma and the interleukine-12, aors that the Th2 cells produce interleukine-4, interleukine-5 and interleukine-13.
  • the TH storage cells are specific to the antigen which they met in first and can be implemented at the time of the secondary immunizing response.

The surface of the majority of the TH cells has the protein CD4, which is attracted towards portions of the molecule of Class II MHC. This affinity implies an intimate connection between the TH cell and the cell-target aucours of antigen-specific activation. The TH cells which have protein of surface CD4 are called cells CD4+ You . A fall of the population of (cells) CD4 is the primary education mechanism by which HIV causes the AIDS.

Random links:List primacies of the Catholic church chaldéenne | Amenardis II | Défarde | Etienne Gourmelen | Hebraic university of Jerusalem | Séquoia,_New_York