Of Organic chemistry, the reduction of Clemmensen consists of the reduction of the aliphatic or aromatic carbonyl compounds in hydrocarbons saturated in the presence of Zinc (Zn) amalgamated with the mercury (Hg) and of Hydrochloric acid (H+; Cl-) concentrate.

When they are not very water soluble substances, one adds, in the reactional medium, a water soluble solvent like the ethanol.

The reduction of Clemmensen is particularly valid for the hydrocarbon synthesis to many odd carbons where the reaction of Wurtz is not applicable.

octan-2-one --> N-octane +H2O

heptan-4-one --> n-heptan +H2O

dibenzylcétone --> dibenzylpropane +H2O

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