Purin
The purin is a nitrogenized Molécule Hétérocyclique obtained by reaction of a molecule of Pyrimidine and of a molecule of Imidazole.
The general term purins indicates also the derivatives of purin and its Tautomère S. Two of the bases of the nucleic acid is purins: the Adénine and the Guanine. In DNA, these bases form hydrogen bonds with their Pyrimidine S complementary, the Thymine and the Cytosine:
In ARN, the complement of the adénine (A) is the Uracile (U) instead of the Thymine:
The Xanthine, the Hypoxanthine, the Theobromine, the Cafeine and the Uric acid are other purins.
Purins, in addition to being components of the DNA and ARN, are in important Biomolécule S, such as ATP, GTP, cyclic AMP, NADP, or Coenzyme has.
Metabolism
The metabolic ways of many organizations make it possible to synthesize and break purins.
Food sources
Purins are in great quantities in the meat, in particular in the liver and the kidneys. The food modes vegetarians bring small quantities of purins.
History
It is the German chemist Hermann Emil Fischer which gave its name to purin in 1884. It synthesized it in 1898. It as showed as the purins belong to the same chemical family.pathology
The drop: it is a pathology which results from a disorder of the degradation of purins which involves an accumulation of uric acid in plasma. This acid is coupled with sodium what forms soda urate crystals which are stored in the synovial liquid of the articulations
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