Portal vein
The portal vein is a Veine which brings blood coming from the digestive bodies (Intestin S, etc) towards the Foie, from where it will arise, after treatment, by the know-hepatic vein. In other words, the liver is located between two veins (in addition to the hepatic artery), which is rather rare in Anatomie Mammifères, one speaks about Système carries.
The portal vein is formed of the meeting of the spléno-mésaraïque trunk (confluent of the splenic Veine and the lower mesenteric Veine) and of the higher vein Mésentérique. It is divided into two branches left and right-hand side which penetrate in the liver by the hepatic Hile.
Physiological consequences
The fact that the liver milked, as of the first passage, the Sang containing the products of the Digestion allows an important detoxication of dangerous substances.
Consequences into therapeutic
Many drugs are degraded in significant proportions by this Effet of first passage hepatic.In order to avoid this degradation, one manages certain substances by a way able to join general circulation without passing by the filter of the liver. Let us quote the way Sublingual E and the way Percutané E.
- AMVF - Association of the Patients of the Vessels of the Liver
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