Poliovirus
The poliovirus belong to the kind Enterovirus. The human poliovirus is the agent responsible for the Poliomyélite.
They are viruses with ARN simple linear bit of positive polarity, i.e. their genome is in the form of a molecule of ARN.
The polioviruses are transmitted by oral way and multiply in amygdalae and fabrics lymphoid of the digestive tract. The virus not wrapped is resistant to digestive solvents. Incubation is from 10 to 14 days.
The adsorption of the poliovirus on the surface of the cell-host is done via the receiver PVR, specific receiver of this virus. This receiver is present at the membrane of many cellular types, but the poliovirus can multiply only in the cells of the former horn of the spinal-cord. The virus penetrates in the cell-host by a process of endocytose.
The expression and the replication of the viral genome take place within the cytoplasm and allow the formation of many viral particles. During these processes, there is diversion of the cellular machinery to the profit of the virus. The viral particles will be released with the favor of a cellular lysis.
The polioviruses are relatively stable viruses: they remain a long time inactivated by pasteurization. The only known natural basin for the Polioviruses is the man.
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