Phenazone

The phenazone is a Analgésique

Chemical formula

1,2-dihydro-1,5-dimethyl-2-phényl-3H-pyrazole-3-one

Synonyms

Analgésine, Antipyrin, Diméthyloxyquinazine, Oxydiméthylquinazine, Oxydiméthylquinizine, Pyrazoline

N° CASE

60-80-0 DCI: PHENAZONE

Code ATC

N02BB01

Principal salts or derived

Phenazone salicylate, phenazone Thymonucléate, Propyphénazone, iodized phenazone, phenazone gentisate

Chemical classes

  • Pyrazole
  • Pyrazolinone

Pharmacological properties

  • Analgesic
  • Antipyrétique
  • Antiinflammatoire (AINS)

Mechanisms of action

Peripheral action analgesic and antipyretic action of aspirine type. Inhibition of the synthesis of prostaglandins and the release of the bradykinine.

Side effects

  • allergic Reaction (Allergy to pyrazolones)

  • Nauseas
  • convulsives Crises
  • haemolytic Agranulocytose
  • Anemia
  • Erythema
  • Urticaria
  • Kératoconjonctivite
  • Reduction in the vision
  • Coloring brown-red of the urine

Routes of administration

  • Oral

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