Néostigmine
see also: Etymology of Néostigmine
The néostigmine is a Parasympathomimétique, inhibiter of the Cholinestérase S marketed under the name of Prostigmine ®. By potentiating the concentration of the Acetylcholine in the synaptic slit, the néostigmine stimulates indirectly at the same time the receivers nicotinic S and muscarinic S.
Clinical use
The néostigmine is indicated in the treatment of the Myasthénie, the Syndrome of Ogilvie and systematically in General anesthesia for antagoniser the effects of the curares not-depolarizers at the end of the intervention, sometimes to treat a acute Rétention of urine. Because of his cholinergic effects (bradycardia, sweats, sialorrhée, diarrhea) one frequently associates it with the Atropine.
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