Lines of Blaschko

the lines of Blaschko is the name given to a cutaneous phenomenon extremely rare which appears at the human being and which produces marblings with characteristic reasons on the skin. These lines were mentioned for the first time in 1901 by the German dermatologist Alfred Blaschko.

They are not limited to a specific disease and alone do not constitute the harbingers of a pathology. At the man, the lines of Blaschko are the result of a data in DNA. At a normal man, the pigmentation of the skin is uniform and the lines are not visible. Skin diseases can however reveal them. One observes then at the patient of the differences in color more or less marked between several parts of the body with characteristic reasons, bands and lines. Most of the time, these reasons resemble a letter V aligned on the axis of the Dos and a letter S on the chest, the Estomac and the sides of the body. These lines follow neither the nervous system, nor the vessels or the lymphatic system. Blaschko had put forth the assumption that the regularity of these reasons between the patients let suppose the presence of an embryonic origin .

These reasons appear also in the case of a Mosaïcisme, i.e. the presence in the same organization of cells with two Génotype S different. One counts approximately 30 cases at the human being in the world.

Anecdote

In the last episode ( Murder with double code ) of the fourth season of the Expert Las Vegas, Grissom discovers lines of Blaschko on the back of a suspect. After first analyzes which had put it out of cause, a new analysis DNA proves that its body comprised two DNA different (dream).

According to Dr. Starr of the University Stanford, the use of a ultraviolet light makes it possible to detect the reason when its contrast is too weak.

External bonds

  • Illustrations showing the various types of reasons
    • Photo
  • of the back of a young patient presenting the reason characteristic in '' V ''
  • Answer of a geneticist about the episode of the Experts
  • Description of the lines of Blaschko

References

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