Leucopenia

A leucopenia is a fall of the number of Leucocyte S totals (i.e. of white globules)) in blood (less than 4000 éléments/mm ³ or 4 billion/liters).

Terminology

The white globules being made up partly of Granulocyte S (or polynuclear) and of Lymphocyte S, following the line reached, one speaks about:

If leucopenia is associated with a Anémie or a Thrombopénie (lowers red globules or plates), one speaks then about bicytopénie .

If the three lines are lowered (leucopenia + weakens + thrombopénie), one speaks then about Pancytopénie.

The opposite of a leucopenia is a Hyperleucocytose.

Possible causes

  • Toxic:
  • infectious
  • deficit of production: disease of osseous marrow
  • local or total irradiation with effects with threshold:

    • < 0,25 Sv: reversible leucopenia
    • 0,25 to 1 Sv: leucopenia
    • 4 to 5 Sv: proportion mortal

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