Laki-Lorand factor

The factor XIII fibrin stabilizing Factor --> is a Enzyme () of the blood Coagulation which ramifies the Fibrine. After the Thrombine converted the Fibrinogène into Fibrine, this last form a protéinacé network in which each unit E is laterally dependant on only a unit D. factor XIII is activated by thrombin in XIIIa factor; its activation in XIIIa factor requires ions calcium like cofactor.

It is also called factor Laki-Lorand or factor of stabilization of fibrin .

Enzyme

Gene S for which different are one Chromosome S:
  • has subunit (6p25-p24). The Transglutaminase share; this adds year alkyl group to the nitrogen one has Glutamine residue, which binds in turn with has Lysine one the other chain.
  • B subunit (1q31-q32.1). This has No clear enzymatic activity, and may serf ace has carrier for the has subunit.
-->

Role in the diseases

A deficiency in factor XIII is very rare, and can cause a serious predisposition to the serious hemorrhages.

External bonds

  • (sub-unit A) and (sub-unit B)
  • deficiency in factor XIII

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