Homozygote

The homozygote is an individual of which both Allèle S located on same the Locus of same a Chromosome (or homologous Chromosome) are identical.

The individuals homozygotes give a population of descendants identical to themselves with regard to the character considered, one then speaks about pure line .

At the human one, the reproduction homozygote is impossible.

Use of the term

The carrying term homozygote is used as much in Physiologie as in Pathologie.

In physiology

  • the Phénotype Groupe Rhesus of the blood groups is either positive or negative. The negative allele being recessive, the phenotype Rh negative corresponds to two negative alleles. In the event of pregnancy at a woman Rh negative with a procreator Rh negative, the children all will be Rh negatives.

In pathology

  • In the event of disease with dominant Transmission autosomic, the sick person is homozygote (what is very rare) that is to say Hétérozygote.
  • In the event of disease with recessive autosomic Transmission, the sick person is always homozygote.

Sources

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