She married in 1442 Jean II of Lusignan (1418 † 1458) king de Chypre and had:
- Charlotte (1443 † 1487), queen of Cyprus
- Cléopha, dead young
Before his marriage, Jean II had had of a connection with Mariette de Patras a son Jacques '' bastard the ''. The hatred of Helene on the mistress and the son, and it made cut the nose of Mariette. To protect his son, Jean II made it renter in the clergy and he was established archbishop of Nicosie at the six years age. But the intrigues did not stop and Jacques, appearing precursory prelates of the Renaissance, did not hesitate to make assassinate two partisans of the queen.
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