GenBank

The GenBank is a American Banque of genes in free access of all the sequences of Nucléotide S publicly available and of their translation in Protéine S. This database was created with the national center for biotechnological information (NCBI) within the framework of the international collaboration on the sequencing of the nucleotides (INSDC according to the English initials). GenBank and its collaborators receive sequences produced in laboratories of the whole world from more than 100.000 different organizations. GenBank continues to grow bigger atan exponential rate, doubling of size every ten months. Release 155, gone back to August 2006, contained more than 65 billion nucleotide bases in more than 61 million sequences. GenBank is built either by direct deposits coming from laboratories, or of deposits in mass of the centers of sequencing to large scales.

The direct deposits in GenBank are done via BankIt, which is a form Internet, or by the autonomous program of deposit, Sequin. To the reception of the deposit of a sequence, the team of GenBank allots a Sequence number to the sequence and carries out controls of quality assurance. The deposits are then registered in the public database, which one can consult the entries by Entrez or download them by ftp. The deposits in mass of data Expressed Sequence Tag (IS), Sequence Tagged Site (STS), Genome Survey Sequence (GSS) and High-Throughput Genome Sequence (HTGS) are generally transmitted by the centers of sequencing to large scales. The direct deposits of group in GenBank also treat complete sequences of microbial genomes.

History

Walter Goad of Theoretical Biology and Biophysics Group with the National laboratory of Los Alamos (LANL) created with others, in the years 1970, the gene bank of Los Alamos, which culminated in 1982 with the creation of the public gene bank founded by the national institute of Health. The LANL collaborated in the GenBank project with the companies Bolt, Beranek and Newman, and with the end of the year 1983 more than 2000 sequences had been recorded there. In the middle of the years 1980, the company Intelligenetics bioinformatics of the Université Stanford ensured the direction of the GenBank project. Being one of the first projects of community Bio-data processing on Internet, the GenBank project launched forums BIOSCI /Bionet to promote the communications in free access between biologists. From 1989 to 1992, the GenBank project forwarded by the National center for biotechnological information lately created.

See too

External bonds

GenBank
BankIt
Sequin

Random links: