Defecto cristalográfico
The renin (also called angiotensinogénase ) is a Enzyme Système renin-angiotensin-aldosterone.
History
The renin was discovered by Tigestedt in 1898.System renin-angiotensin-aldosterone
The synthesis of the renin by the cells of the juxta-glomerular apparatus renal is carried out in answer to:
- a lowers pressure of blood perfusion,
- with a Hypokaliémie,
- with a Hyponatrémie.
The renin is a long protein of 340 amino-acid and of a molecular weight of 37 let us kDaltons. The Gène of the renin is located on the long arm of the Chromosome 1 (1q32).
Its role is to catalyze the transformation of the angiotensinogene (Protéine synthesized by the Foie) into angiotensin I which will give itself angiotensin II, peptide involving an increase in the Volémie while exploiting the feeling of thirst, the secretion of Aldostérone, and gauges it blood-vessels.
Inhibiters of the renin
the Aliskirène is a specific inhibiter of the renin. It makes it possible cause a drop in the blood Pressure among hypertensive patients .| Random links: | Aken | Laser | Préneron | Betty White | Pramaggiore | Most off the best |