Cross study plan

The Study plan cross (in English Crossover Study Design ) is a type of estimate or protocol of research which implies the administration of one or more Traitement S (or Thérapie S) in a consecutive way to the same group of subjects. The order of administration of the treatments can be predetermined or random.

This protocol suffers from two disadvantages:

On the one hand, it with the effect of order (order in which the treatments are managed) effect '' which can influence the results (for example, a drug having several side effects taken by a group of people can there generate a greater sensitivity to side effects at the time of the administration of a second drug of which the side effects are however much less important).
In addition, it there with the effect of carryforward effect '' (for example, a complex task presented to a group of subjects can limit the effectiveness of these same subjects at the time one second however tries simpler).

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