Cálculo de la lambda

This article treats only infection caused by “ Chlamydia trachomatis”

One usually indicates under the term of chlamydiose the genital infections in connection with the infectious agent Chlamydia trachomatis. They are the Sérotype S D with K of the Chlamydia trachomatis which are responsible for infections sexually transmissible. This bacterium is with strict inter-human transmission. Same the sérotypes of chlamydia trachomatis can cause Conjonctivite S.

4% of the young people at least are reached, leading certain countries to make a systematic Dépistage because of the costs of the complications of the genital infection with Chlamydia trachomatis responsible for Infertilité by destruction of the epithelium of the horn involving an increase in the number of extra-uterine pregnancies.

This infection is generally quiet and it is not that during the investigations carried out within the framework of an assessment of an infertility that this infection (or at least its after-effects) is discovered.

Fortunately, for a few years the diagnosis has been largely facilitated by the direct research of the nucleic acid of the bacterium by genic amplification (PCR).

Epidemiology

It is most frequent of the infections sexually transmissible Bactérie.
  • This infection is frequent at the young credits sexually:
    • the cases are most numerous among women from 15 to 24 years (incidence among women from 15 to 19 years: 1  109,1/100  000 inhabitants; among women from 20 to 24 years: 1  041,7/100  000 inhabitants).
    • at the men, of many cases is not diagnosed.
  • More than 50% of the men and 70% of the women can be asymptomatic.
  • At the symptomatic cases, the incubation period varies between 2 and 6 weeks, but it can be longer.
  • Neisseria gonorrhoeae is occasionally associated with Chlamydia trachomatis .
  • a symptomatic chronic infection is possible.
  • generally Reaches a young credit sexually old of less than 25 years

Clinical signs

At the man

  • Secretion at the end of the Rod.
  • Dysurie
  • Feeling of tingling on the level of the Urethra
  • Pains with the Testicle S
small red button

At the woman

  • generally asymptomatic Infection
  • genital Flow with the curdled milk aspect and yeast odor
  • Dysurie after having eliminated a urinary Infection
  • low abdominal Pains
  • abnormal vaginal Bleedings
  • Dyspareunie deep
  • Pains during the rules

Manifestations of the disease

Women

Men

Men and women

Complications

At the woman
  • high genital Infection being able to involve the sterility or of the extra-uterine pregnancies
  • chronic pelvic Pain
  • Syndrome of Reiter

At the newborn in an expectant mother carrying chlamydiose

At the man

Diagnosis

Method of choice: Direct research of the nucleic acids of the bacterium by genetic amplification.

  • Can be practiced on a simple jet of Urine at the man or at the woman
  • Can be also made on a taking away on the level of the Endocol or Urètre at the man.
  • the sample must include epithelial cells, because it is an obligatory intracellular bacterium. Genital secretions can not contain a great number of these cells.
  • In France, the S.S refunds only research on one site (does not refund a research in the urines and in a taking away of the endocol). The cost of this examination is of 23 € (2005)

Other methods

Serology
  • does not contribute to the diagnosis of the low infections with Chlamydia trachomatis .
  • Is seldom useful in the diagnosis of the pelvic infections at the woman
Cellular culture
  • remained a long time the method of reference
  • Nécessite a taking away rich in cell (plastic flue brush)
  • Absolue need for a perfect technique of taking away and transport

Detection of the chlamydial antigens

Treatments

The treatment of the noncomplicated chlamydiose rests on:
Treatment of choice
Alternatives

Monitoring
  • Preventive during the treatment and 7 days after, is 7 days in the event of monodose treatment, 14 for a " treatment; classique"
  • Research and treatment of partners the last two month old
  • PCR (genic amplification) of control of the cure one month after the end of the treatment
  • Serology without interest

Prevention

  • Existence of systematic policy of tracking of the Chlamydia trachomatis in the countries of Northern Europe by research of the chlamydia in the urines at the time of the university inscription
  • In 2003, the National agency for the evaluation of health concludes that tracking is justified even in the absence of clinical signs the dispensaries antivénériens, the public health clinics free anonymity and of the AIDS, the centers of planning and family education and the centers of I.V.G among women of less than 25 years.

Photographs

See too

  • venereal Lymphogranulomatosis or Disease of Nicolas Favre due to the sérotypes L1 L2 and L3

More images are available in our database images

Sources

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