Basophilic Granulocyte
The basophilic granulocytes or polynuclear basophilic (or more simply “ basophilic ”) are Leucocyte S (blood cells of the white line), having a role in the Immune system. One calls them polynuclear because of an historical error: of share the lobed character of their core (two lobes in general), one believed a long time that these cells had several cores. The qualifier of “basophilic” also comes from a visible characteristic in optical microscopy: after addition of the usual vital dyes, these cells are coloured in blue (their great cytoplasmic inclusions fix the blue dyes). The others granulocytes are the eosinophilic granulocytes neutrophiles and .
The basophilic ones are rarest (0.5%) Granulocyte S. cytoplasmic inclusions contain many chemical molecules, and in particular Histamine, Sérotonine, and Héparine. The Histamine and the Héparine are used to prevent coagulation in the blood-vessels, but also to increase the permeability of the Capillaires, thus opening the way with the Diapédèse.
Histamine activates the inflammatory reaction and also intervenes in the allergic reactions .
When they leave the vessels to join fabrics, the basophilic ones are transformed into Mastocyte S. These cells activated play a part major in the Inflammation, able to salt out their vacuoles in contact with Allergène S to which they are sensitive.
| Random links: | Jean-Paul Chanois | Wolfgang Perner | Price of the General governor 1963 | Taglio di Po | Hans Plotz | Acide_cétonique |