Bartolomeu Perestrelo (towards 1395 - 1457) - or Pedro Moniz Perestrelo - is a navigator and Explorateur Portuguese.

Resulting from a family of Italian nobility, it was, with João Gonçalves Zarco and Tristão Vaz Teixeira one of the discoverers of the islands of Madeira and Oporto-Santo and with them began their colonization in 1419-1420.

It was named captain-governor of Oporto-Santo, while Zarco and Vaz divided the Madeira. Its field was poorest of the three, and became it still more because, according to the tradition, a full lapine would have escaped on the island at the time of one of its unloadings, and the rabbits are reflected to pullulate, eliminating the thin vegetation which the island had.

One of his/her daughters, Felipa Perestrello Moniz (born about 1455) married Christophe Colomb in 1479 during a stay of this one in Madeira and Oporto-Santo. His wife brought in dowry, in particular, all the charts of the winds and the currents of the Portuguese possessions of the Atlantic which belonged to his/her father, and these charts probably helped Christophe Colomb in his discovery of the New-World.