Acid tétradécanoïque
The tétradécanoïque acid or myristic acid , is a Fatty-acid saturated common present in the dairy products. Rough chemical formula:
CH3 (CH2) 12COOH.
The reduction of the myristic acid gives the myristylic Alcool.
Like many fatty-acids, the myristic acid intervenes in the composition of the plasmic Membrane of the cells eucaryotes, made of a lipidic Bicouche. On the intracellular face of the plasmic membrane, the myristic acid can interact with Protéines; one speaks then about Myristilation. This acid binds in a covalent way to the level of nitrogen of a residue glycine in position 2 in the polypeptide chain of protein. This intrinsic protein is then known as Enchassée (see also the Prénylation and the Palmitylation).
is also commonly added to has penultimate Nitrogen terminus Glycine in receptor-associated kinases to confer the membrane localization off the enzyme. this is achieved by the Myristic acid having a rather important Hydrophobicité to become incorporated into the fatty acyl core off the double-layered Phospholipid off the plasma membrane of the cells Eucaryote S. -->
External bonds
- Image off Chemical Structure
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